Proton therapy for reirradiation
Reirradiation increases risks of short- and long-term radiation-related side effects1,2. Contrary to conventional X-ray therapy, protons have the ability to aim a higher dose of radiation directly inside the tumor and to spare surrounding healthy tissue, which means they can be used for reirradiation of almost any disease site. Patients with recurrent disease who had received prior radiotherapy are good candiates for proton therapy that targets tumors precisely while limiting radiation exposure to healthy tissues. Proton therapy may improve treatment outcomes in patients with recurrent tumors3.
References
- Janot, F., de Raucourt, D., Benhamou, E., Ferron, C., Dolivet, G., Bensadoun, R. J., Hamoir, M., Géry, B., Julieron, M., Castaing, M., Bardet, E., Grégoire, V., & Bourhis, J. (2008). Randomized trial of postoperative reirradiation combined with chemotherapy after salvage surgery compared with salvage surgery alone in head and neck carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 26(34), 5518–5523.
- Nieder C. Second re-irradiation: a delicate balance between safety and efficacy. Physica Medica. 2019 Feb 1;58:155-8.
- Simone II CB, Plastaras JP, Jabbour SK, Lee A, Lee NY, Choi JI, Frank SJ, Chang JY, Bradley J. Proton reirradiation: Expert recommendations for reducing toxicities and offering new chances of cure in patients with challenging recurrence malignancies. InSeminars in radiation oncology 2020 Jul 1 (Vol. 30, No. 3, pp. 253-261). WB Saunders.
What they say about it
Frequently asked questions
In this website, we provide you with extensive literature and documents about PT research and indications. In particular, we've compiled a series of in-depth white papers exploring the various types of cancers for which proton therapy could be a viable first-choice option.
Proton therapy is indicated in an increasing number of types of tumors. To know more about proton therapy therapy's efficiency and indications, consult our pages on how to start a treatment and the different types of cancers in which oncologist choose proton therapy as a first-choice treatment.
Proton Therapy is indicated in an increasing number of types of tumors. As it minimizes...