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Genito-urinary cancer

Proton therapy to treat genito-urinary cancers

Prostate cancer is the second most frequent in men worldwide1, traditional radiation treatment carries the risk of serious toxicity due to the proximity of important nerves, the rectum and the bladder2. By targeting the tumor, proton therapy can decrease the risk of damage to surrounding organs. It lowers the risk of damaging healthy tissue and provides patients with better quality of life. Gynecological cancers such as cervical, endometrial, uterine, vaginal and vulvar cancer can also be good indications for proton therapy. As it allows for higher doses of radiation to be delivered to the tumor without damaging surrounding healthy tissue and organs, Proton therapy is an established and efficacious treatment for localized prostate cancer that achieves highly effective tumor control with excellent toxicity outcomes and patient quality of life comparable to advanced radiotherapy techniques. For selected patients such as patients with high-risk disease, node-positive disease or recurrent disease, proton therapy offers potential for reduction in short- and long-term side effects by minimizing radiation dose to healthy tissues.3 Protons may also help spare hormone function in younger women by preserving the ovaries.

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References

  1. Rawla P. Epidemiology of prostate cancer. World journal of oncology. 2019 Apr;10(2):63.
  2. Michaelson MD, Cotter SE, Gargollo PC, Zietman AL, Dahl DM, Smith MR. Management of complications of prostate cancer treatment. CA: a cancer journal for clinicians. 2008 Jul;58(4):196-213.
  3. Efstathiou, J.A. et al. Prostate Advanced Radiation Technologies Investigating Quality of Life (PARTIQoL): Phase III Randomized Clinical Trial of Proton Therapy vs. IMRT for Localized Prostate Cancer. 
    International Journal of Radiation Oncology, Biology, Physics, Volume 120, Issue 2, S1

Frequently asked questions

How can I know more about the indications of proton therapy?

In this website, we provide you with extensive literature and documents about PT research and indications. In particular, we've compiled a series of in-depth white papers exploring the various types of cancers for which proton therapy could be a viable first-choice option.

 
Know more about proton therapy's efficiency

Proton therapy is indicated in an increasing number of types of tumors. To know more about proton therapy therapy's efficiency and indications, consult our pages on how to start a treatment and the different types of cancers in which oncologist choose proton therapy as a first-choice treatment.

 
What types of cancers does proton therapy treat best?

Proton Therapy is indicated in an increasing number of types of tumors. As it minimizes...

 

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